Continuous Ketone Monitoring & Metabolic AI

Verify your fast.
Track your ketosis.
Master your metabolism.

Make metabolic first principles a way of life.

MetaTwin integrates with Sibio's CKM technology to deliver effortless, around-the-clock ketone tracking — so you can precisely measure how well your intermittent fasting drives daily metabolic switching, without changing a thing about your routine.

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Continuous Ketone Monitoring — verified by MetaTwin

MetaTwin is a specialised tool for verifying how effectively daily intermittent fasting drives metabolic switching. Integrated with Sibio's CKM technology, the platform delivers effortless, around-the-clock real-time tracking of your personal ketone dynamics.

Metabolic health lifestyle — morning light

"Metabolic flexibility is not a destination — it's the rhythm your body learns to keep."

Intermittent Ketosis is the validation of intermittent fasting.

At MetaTwin, we believe that true longevity begins with biological clarity. We bridge the gap between rigorous metabolic science and daily human behaviour by making Intermittent Ketosis (IK) measurable and actionable. Through effortless, continuous ketone monitoring, we empower individuals to master their daily intermittent fasting windows — not as a restriction, but as a precise tool to unlock metabolic flexibility. By capturing the subtle dynamics of nutritional ketosis in real time, MetaTwin helps the body effortlessly switch between fuel sources, supporting daily lipid oxidation and shifting metabolic health from a conscious effort to an instinctual habit.

Precision fasting,
quantified ketosis

The MetaTwin software quantitatively measures the daily cumulative duration of nutritional ketosis, enabling users to precisely execute metabolic switching through fasting — enhancing metabolic flexibility and facilitating daily lipid oxidation.

  • 24-hour real-time continuous ketone monitoring (CKM)
  • Daily ketosis duration quantification — know exactly how long you stayed in fat-burning mode
  • Intermittent fasting verification — data-driven metabolic switching feedback
  • AI-powered metabolic pattern recognition & personalised fasting recommendations
  • Secure cloud sync — iOS & Android
Sensor type
Sibio CKM — Continuous Ketone Monitoring
Wear duration
Up to 14 days continuous wear
Platform
MetaTwin App — iOS & Android
Certifications
CE marked · ISO 13485
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Download the App

Scan to install MetaTwin on iOS or Android

Metabolic health foods — avocado, salmon, nuts

Metabolic nutrition · Fat-adapted fuelling · Ketogenic whole foods

01

Wear & Sense

Apply the Sibio CKM sensor to your upper arm. Ketone levels are sampled continuously, 24 hours a day, for up to 14 days — capturing your full fasting and feeding cycle.

02

Verify & Quantify

The MetaTwin app quantifies your daily cumulative duration of nutritional ketosis. See exactly how your intermittent fasting protocol is performing — day by day, hour by hour.

03

Act & Optimise

AI-driven insights help you fine-tune your fasting window, meal timing, and lifestyle factors to maximise metabolic flexibility and daily lipid oxidation — grounded in your own data.

Hardware

Sibio CKM Sensor — Engineered for precision

The world's first 14-day continuous ketone monitor. Precision electrochemical sensing, effortless 24/7 wear, and seamless Bluetooth connectivity to the MetaTwin platform.

Sibio CKM Blood Ketone Sensor Packaging
Sensor Life
14 days continuous monitoring
Sampling Rate
Real-time, every 5 minutes
Biomarker
Beta-Hydroxybutyrate (BHB)
Water Resistance
IPX8 — shower & swim safe

Science

The science of metabolic switching

Intermittent fasting triggers a fundamental metabolic shift: the body transitions from glucose-based to fat-based energy production. This process — metabolic switching — produces ketone bodies (primarily beta-hydroxybutyrate, BHB), signalling that lipid oxidation is under way.

MetaTwin quantifies this switch. By continuously tracking BHB levels via Sibio's CKM sensor, the platform measures exactly when you enter nutritional ketosis, how long you stay there, and how effectively your fasting window drives daily fat oxidation.

Why 16:8 doesn't work the same for everyone

Not everyone who follows a 16-hour fasting window actually enters nutritional ketosis — and the ones who don't are unlikely to experience the cellular renewal effects that make intermittent fasting worth doing. According to the cyclic metabolic switching framework proposed by Mattson (2025), the metabolic benefits of intermittent fasting are contingent on the body completing a genuine fuel-source transition — from glucose to ketones — during each fasting cycle. Without this switch, the fasting window functions merely as caloric restriction, not as a trigger for metabolic flexibility or autophagy-related renewal processes. MetaTwin addresses this directly: rather than assuming a fixed fasting window is sufficient, it continuously tracks whether ketosis actually occurs and quantifies the cumulative daily ketosis duration — turning an invisible biological event into a measurable personal metric.

Reference: Mattson, M. P. (2025). The cyclic metabolic switching theory of intermittent fasting. Nature Metabolism, 7(4), 665–678.

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Continuous Ketone Monitoring

Sibio's CKM sensor tracks BHB in real time, 24 hours a day — the world's first 14-day continuous ketone monitor revealing exactly when your body enters fat-burning mode.

Digital Twin AI

A personalised model trained on your longitudinal ketone data, learning your unique metabolic response to fasting — refined with each new reading.

Ketosis Duration Quantification

MetaTwin measures your daily cumulative nutritional ketosis time — giving you a precise, quantifiable target to optimise your fasting protocol against.

Metabolic Flexibility Scoring

Track how efficiently your body switches between fuel sources over time — the hallmark of true metabolic health.

01

Biosensor Layer

Sibio's precision electrochemical CKM sensor captures interstitial BHB effortlessly, 24/7, for up to 14 days — no fingerpricks, no disruption to daily life.

02

Signal Processing

On-device and cloud algorithms denoise, calibrate and stream continuous ketone data in real time to the MetaTwin platform.

03

Personalised Modelling

Bayesian and deep-learning models create an individual ketone-response fingerprint that updates with every fasting cycle.

04

Clinical Verification

MetaTwin quantifies daily cumulative nutritional ketosis duration — giving users a concrete, trackable metric of how well their fasting window is actually working.

Blog & Insights

From the MetaTwin team

Science notes, product updates and perspectives on metabolic health — written for curious minds.

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Let's build the future of metabolic health together

Whether you're a clinician, researcher, distributor or investor — we'd love to hear from you.

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